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       Motonori Tsuji


 

 

2-105-14 Takasu

Misato-shi, Saitama 341-0037, JAPAN

 

Research Area: Institute of Molecular Function 

 

E-mail: motonori_#_molfunction.com (Please replace "_#_" with "@")

Fax +81 48 956 6985

 

Major Publications and Products (from 2000)

Motonori Tsuji*, Koichi Shudo, Hiroyuki Kagechika. Identifying the Receptor Subtype Selectivity of Retinoid X and Retinoic Acid Receptors via Quantum Mechanics. FEBS Open Bio., 2017, DOI: 10.1002/2211-5463.12188.

Origin of the Receptor Subtype Selectivity via Quantum Mechanics

Motonori Tsuji. Virtual Screening System, Revision G1, Institute of Molecular Function, Saitama, Japan, 2016.

Motonori Tsuji. Docking Study with HyperChem, Revision G1, Institute of Molecular Function, Saitama, Japan, 2016. 

Motonori Tsuji. Homology Modeling Professional for HyperChem, Revision G1, Institute of Molecular Function, Saitama, Japan, 2016. 

Motonori Tsuji. ONIOM Interface for Receptor, Revision G1, Institute of Molecular Function, Saitama, Japan, 2016. 

Motonori Tsuji. Gaussian Interface for Receptor, Revision G1, Institute of Molecular Function, Saitama, Japan, 2016. 

Motonori Tsuji. A Ligand-Entry Surface of the Nuclear Receptor Superfamily Consists of the Helix H3 of the Ligand-Binding Domain. J. Mol. Graph. Model., 2015, 62, 262-275. 

Helix H3 Three-Point Intial Binding Hypothesis

Motonori Tsuji*, Koichi Shudo, Hiroyuki Kagechika. Docking Simulations Suggest that all-trans Retinoic Acid Could Bind to Retinoid X Receptors. J. Comput. Aided Mol. Des., 2015, 29, 975-988. 

New Hypothesis for ATRA Mechanism 

Motonori Tsuji. Geometrical Dependence of the Highest Occupied Molecular Orbital in Bicyclic Systems: p Facial Stereoselectivity of Bicyclic and Tricyclic Olefins. Asian J. Org. Chem., 2015, 4, 659-673. 

(Chosen by Editor) 

Tsuji Model for Facial Stereoselectivity

Motonori Tsuji. Virtual Screening System, Revision G, Institute of Molecular Function, Saitama, Japan, 2015.

Motonori Tsuji. Docking Study with HyperChem, Revision G, Institute of Molecular Function, Saitama, Japan, 2015. 

Motonori Tsuji. Homology Modeling Professional for HyperChem, Revision G, Institute of Molecular Function, Saitama, Japan, 2015. 

Motonori Tsuji. ONIOM Interface for Receptor, Revision G, Institute of Molecular Function, Saitama, Japan, 2015. 

Motonori Tsuji. Gaussian Interface for Receptor, Revision G, Institute of Molecular Function, Saitama, Japan, 2015. 

Motonori Tsuji. Virtual Screening System, Revision F3, Institute of Molecular Function, Saitama, Japan, 2014.

Motonori Tsuji. Docking Study with HyperChem, Revision F3, Institute of Molecular Function, Saitama, Japan, 2014. 

Motonori Tsuji. Homology Modeling Professional for HyperChem, Revision F3, Institute of Molecular Function, Saitama, Japan, 2014. 

Motonori Tsuji. ONIOM Interface for Receptor, Revision F3, Institute of Molecular Function, Saitama, Japan, 2014. 

Motonori Tsuji. Gaussian Interface for Receptor, Revision F3, Institute of Molecular Function, Saitama, Japan, 2014. 

Motonori Tsuji. Local Motifs Involved in the Canonical Structure of the Ligand-Binding Domain in the Nuclear Receptor Superfamily. J. Struct. Biol.,2014, 185,355-365. 

(Top 22th article downloaded for 90 days) 

Folding Mechanism and Agonism and Atagonism Mechanism in Nuclear Receptor

Motonori Tsuji. Virtual Screening System, Revision F2, Institute of Molecular Function, Saitama, Japan, 2012.

Motonori Tsuji. Docking Study with HyperChem, Revision F2, Institute of Molecular Function, Saitama, Japan, 2012. 

Motonori Tsuji. Homology Modeling Professional for HyperChem, Revision F2, Institute of Molecular Function, Saitama, Japan, 2012. 

Motonori Tsuji. ONIOM Interface for Receptor, Revision F2, Institute of Molecular Function, Saitama, Japan, 2012. 

Motonori Tsuji. Gaussian Interface for Receptor, Revision F2, Institute of Molecular Function, Saitama, Japan, 2012. 

Motonori Tsuji. Virtual Screening System, Revision F1, Institute of Molecular Function, Saitama, Japan, 2010.

Motonori Tsuji. Docking Study with HyperChem, Revision F1, Institute of Molecular Function, Saitama, Japan, 2010. 

Motonori Tsuji. Homology Modeling Professional for HyperChem, Revision F1, Institute of Molecular Function, Saitama, Japan, 2010. 

Motonori Tsuji. ONIOM Interface for Receptor, Revision F1, Institute of Molecular Function, Saitama, Japan, 2010. 

Motonori Tsuji. Gaussian Interface for Receptor, Revision F1, Institute of Molecular Function, Saitama, Japan, 2010. 

Motonori Tsuji.  Homology Modeling Professional for HyperChem Reference, Institute of Molecular Function, pp1-22, 4th ed., 2010.

Motonori Tsuji. Docking Study with HyperChem Manual, Institute of Molecular Function, pp1-108, 5th ed., 2010.

Motonori Tsuji. Homology Modeling Professional for HyperChem Manual, Institute of Molecular Function, pp1-133, 6th ed., 2010.

Motonori Tsuji.  Homology Modeling Professional for HyperChem Reference, Institute of Molecular Function, 3th ed., 2009.

Motonori Tsuji. Docking Study with HyperChem Manual, Institute of Molecular Function, 4th ed., 2009.

Motonori Tsuji. Homology Modeling Professional for HyperChem Manual, Institute of Molecular Function, 5th ed., 2009.

Motonori Tsuji.  Homology Modeling Professional for HyperChem Reference, Institute of Molecular Function, 2nd ed., 2008.

Motonori Tsuji. Docking Study with HyperChem Manual, Institute of Molecular Function, 3th ed., 2008.

Motonori Tsuji. Homology Modeling Professional for HyperChem Manual, Institute of Molecular Function, 4th ed., 2008.

Motonori Tsuji. Virtual Screening System, Revision E1 and E2, Institute of Molecular Function, Saitama, Japan, 2008.

Motonori Tsuji. Docking Study with HyperChem, Revision E1 and E2, Institute of Molecular Function, Saitama, Japan, 2008. 

Motonori Tsuji. Homology Modeling Professional for HyperChem, Revision E1 and E2, Institute of Molecular Function, Saitama, Japan, 2008. 

Motonori Tsuji. ONIOM Interface for Receptor, Revision E1 and E2, Institute of Molecular Function, Saitama, Japan, 2008. 

Motonori Tsuji. Gaussian Interface for Receptor, Revision E1 and E2, Institute of Molecular Function, Saitama, Japan, 2008. 

Motonori Tsuji. Development of the Structure-based Drug Design System, HCHC and DSHC. Mol. Sci. 2007, 1, NP004. 

Motonori Tsuji.  Homology Modeling Professional for HyperChem Reference, Institute of Molecular Function, 1st ed., 2007.

Motonori Tsuji. Docking Study with HyperChem Manual, Institute of Molecular Function, 2nd ed., 2007.

Motonori Tsuji. Homology Modeling Professional for HyperChem Manual, Institute of Molecular Function, 3th ed., 2007.

Motonori Tsuji. Virtual Screening System, Revision C1, C2, and D1, Institute of Molecular Function, Saitama, Japan, 2007.

Motonori Tsuji. Docking Study with HyperChem, Revision C1, C2, and D1, Institute of Molecular Function, Saitama, Japan, 2007. 

Motonori Tsuji. Homology Modeling Professional for HyperChem, Revision C1, C2, and D1, Institute of Molecular Function, Saitama, Japan, 2007. 

Motonori Tsuji. ONIOM Interface for Receptor, Revision C1, C2, and D1, Institute of Molecular Function, Saitama, Japan, 2007. 

Motonori Tsuji. Gaussian Interface for Receptor, Revision C1, C2, and D1, Institute of Molecular Function, Saitama, Japan, 2007. 

Motonori Tsuji. Rational Drug Design for Organic Chemists. Institute of molecular Function, 2006. 

Motonori Tsuji. Seitaikoubunnshi niokeru Sougosayoubui no Yosokuhouhou. JP, Patent 2006-125188, 2006. 

Motonori Tsuji. Docking Study with HyperChem Manual, Institute of Molecular Function, 1st ed., 2006.

Motonori Tsuji. Homology Modeling Professional for HyperChem Manual, Institute of Molecular Function, 2nd ed., 2006.

Motonori Tsuji. Virtual Screening System, Revision A2 and B1, Institute of Molecular Function, Saitama, Japan, 2006.

Motonori Tsuji. Docking Study with HyperChem, Revision A2 and B1, Institute of Molecular Function, Saitama, Japan, 2006. 

Motonori Tsuji. Homology Modeling Professional for HyperChem, Revision B1, Institute of Molecular Function, Saitama, Japan, 2006. 

Motonori Tsuji. ONIOM Interface for Receptor, Revision B1, Institute of Molecular Function, Saitama, Japan, 2006. 

Motonori Tsuji. Gaussian Interface for Receptor, Revision B1, Institute of Molecular Function, Saitama, Japan, 2006. 

Motonori Tsuji. Homology Modeling Professional for HyperChem Manual, Institute of Molecular Function, 1st ed., 2005.

Motonori Tsuji. Homology Modeling Reference for HyperChem, Institute of Molecular Function, 1st ed., pp1-66, 2005.

Motonori Tsuji. Homology Modeling Professional for HyperChem, Revision A3, Institute of Molecular Function, Saitama, Japan, 2005. 

Motonori Tsuji. ONIOM Interface for Receptor, Revision A3, Institute of Molecular Function, Saitama, Japan, 2005. 

Motonori Tsuji. Gaussian Interface for Receptor, Revision A3, Institute of Molecular Function, Saitama, Japan, 2005. 

Motonori Tsuji. Most Stable Conformation of the Cyclopropane Ring Attached at a Carbon Atom in a 1,2-Dicarba-closo-dodecaborane(12) System. J. Org. Chem., 2004, 69, 4063-4074.

Most Stable Conformation of Cyclopropane Ring

Motonori Tsuji. On Attempts at Generation of Carboranyl Carbocation. J. Org. Chem., 2003, 68, 9589-9597.

Carboranyl Carbocation

Motonori Tsuji. Ab Initio Protein 3D Modeling, Saitama, Japan, 2002. 

Motonori Tsuji. Protein Secondary Structure Prediction, Saitama, Japan, 2002. 

Motonori Tsuji, Yukiko Koiso, Hiroyasu Takahashi, Yuichi Hashimoto, and Yasuyuki Endo. Modulatos of Tumor Necrosis Factor a Production Bearing Dicarba-closo-dodecaborane as a Hydrophobic Pharmacophore. Biol. Pharm. Bull., 2000, 23, 513-516.

 

 


       Society Activities


      

Business Research Institute                                                            2008 -            Special Member

American Chemical Society                                                           2003 -            Regular Member

Japan Society for Retinoid Research                                              1995 -            Regular Member

Society Computer Chemistry, Japan                                              1994 -            Regular Member

The Pharmaceutical Society of Japan                                             1992 -            Regular Member

Japan Society for Bioscience, Biotechnology, and Agrochemistry   1990 - 1995

Pesticide Science Society of Japan                                                 1990 - 1995