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   Last Modified

   15 February 2017

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Bioinformatics

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Structural Bioinformatics

 

ab initio 3D Modeling

The "ab initio 3D modeling" based on the high precision of our secondary structure prediction algorithm

The predicted structures well reproduced the corresponding crystal structures (refer to the results of the protein superposition).  In particular, our algorithm precisely predicted both a loop structure and a random coil structure. Consequently, the secondary structure parts (helices and sheets) are coordinated to a suitable orientation, thus giving a well-reproduced whole structure.

 

Superposition between the Predicted 3D structure and the Corresponding Crystal Structure

 

Secondary Structure Prediction

Novel secondary structure prediction algorithm based on the f and y values of main chain atoms

This algorithm shows the high precision in the known algorithms (e.g., Chou-Fasman and neural network algorithms, etc.).

 

Example of the Secondary Structure Prediction

 

Example of the Secondary Structure Prediction

 

The ab initio 3D Modeling program carries this secondary structure prediction algorithm.

 

 

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